Sumerian Tiamat "shining personification" of the waters.

ENUMA ELISH: THE EPIC OF CREATION

THE FIRST TABLET

When in the height heaven was not named,
And the earth beneath did not yet bear a name,
And the primeval Apsu, who begat them,
And chaos, Tiamut, the mother of them both
Their waters were mingled together,
And no field was formed, no marsh was to be seen;
When of the gods none had been called into being,....

Tiamat was the "shining" personification of salt water who roared and smote in the chaos of original creation. She and Apsu filled the cosmic abyss with the primeval waters. She is "Ummu-Hubur who formed all things". Tiamat possessed the Tablets of Destiny. In the end Tiamat is killed, head crushed and blood poured out and whose body is used to re-create the universe.

The 13th Sign of the Zodiac : Ophiuchus Serpent bearer.

The Astrological Lore of Ophiuchus: Ophiuchus was better known in classical times as Asclepius, [in Latin, Aesculapius] the God of Medicine. He learnt the art from Chiron, the Centaur. On either side of Ophiuchus in the heavens lie the two parts of the sign of the serpent he holds, Serpens Caput, the Serpent's Head and Serpens Cauda, the Serpent's Tail. The twined serpent staff is the badge of the medical profession to this day. [However, the sign of the serpent itself does not form part of the Real Solar Zodiac, though it does from part of the Planetary Zodiac.] It is from the Serpent that Ophiuchus learnt the secret of the Elixir of Life.
The even older Babylonian version is slightly different. Here the serpent is Tiamat, the Monster of the Bitter Ocean. Holding Tiamat is Marduk, the Sun God of the Babylonians. They are doing battle together in the eternal fight of good against evil.